To access our prescription products section, you need to be a member of the healthcare profession because the materials in this area of our website are
specifically prepared for that audience only.
Please click on the appropriate button below to confirm that you are a healthcare professional.
HEAT REALLY WORKS!
This is how bite away® works
bite away®: The original heat pen
bite away® is the original thermal pen for bites and stings which can provide effective and lasting relief of itching from insect bites and stings.
How does bite away® work?
In the case of an insect bite, the insect’s saliva triggers an immune reaction in the skin. Immune cells are activated and a natural chemical histamine is released by the body.
The histamine can then bind to the receptors of the nerve cells. Itching can develop at the affected skin site. bite away® can relieve this reaction with concentrated heat. This is known as local heat therapy which is based upon two possible mechanisms of action.
Mechanism of action 1: Counter irritation with heat stimulus
Through targeted counter-pain by means of heat-related activation of the TRPV-1 receptors, inhibition of the neuronal itch signalling pathway can be achieved.1 Simply put, the application of heat acts like a “counter-irritant” on the nerve cells of the skin. This counter irritation can inhibit the transmission of the itching signal to the brain and thus relieve the sensation and annoyance of itching.
1: Yosipovitch G, Fast K, Bernhard JD. Noxious heat and scratching decrease histamine-induced itch and skin blood flow. J Invest Dermatol. 2005 Dec;125(6):1268-72.
Mechanism of action 2: Decreased histamine release
In addition, there is a second possible mechanism of action. Studies have shown that the application of concentrated heat can have a positive influence on various immune reactions. It is assumed that through inhibition (heat shock) of the mast cells, the release of histamine and other inflammatory mediators is decreased (in vitro).2 A decreased release of histamine can lead to relief of the itching sensation.
2: Greaves MW, Mongar JL. The mechanism of anaphylactic histamine release from rabbit leucocytes. Immunology. 1968 Nov;15(5):743-9.
bite away® applies heat therapy
The original insect bite heat pen applies targeted heat to the skin. In a clinical study with bite away®, it was shown that it can provide lasting relief of itching in just one minute. In a real-life observational study, it was able to be shown that, in general, one application is enough to stop the itching.3
3: Müller C, Großjohann B, Fischer L. The use of concentrated heat after insect bites/stings as an alternative to reduce swelling, pain, and pruritus: an open cohort-study at German beaches and bathing-lakes. Clin Cosmet Investig Dermatol. 2011;4:191-6.
The original heat pen
Get your own bite away® now. After just one application, the original bite-and-sting pen can provide lasting relief of itching from insect bites and stings within one minute. No more creams or annoying smearing. It has a completely chemical-free effect. Designed, engineered & made in Germany.